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Home » Products » Anesthesia Products » Sodium Butyrate Capsules

Sodium Butyrate Capsules

Sodium Butyrate Capsules
Sodium Butyrate Capsules
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Product Code : INV SB05
Brand Name : Sodium Butyrate
Product Description
Uses:

Sodium Butyrate is the sodium salt of butyrate with potential antineoplastic activity. Butyrate, a short chain fatty acid, competitively binds to the zinc sites of class I and II histone deacetylases (HDACs). This binding affects hyperacetylation of histones, resulting in a modified DNA conformation, which subsequently leads to the uncoiling or relaxing of chromatin. Enhanced accessibility of chromatin to transcription-regulatory complexes leads to increased transcriptional activation of various epigenetically suppressed genes. Butyrate, a HDAC inhibitor, induces cell cycle arrest in G1 or G2/M and also increases the expression of other genes and proteins involved in cellular differentiation and apoptotic signaling. Since cancer may be regarded as a disease of differentiation and sodium butyrate induces differentiation of malignant cells in vitro, a study of the clinical pharmacology of sodium butyrate was undertaken. It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including inhibition ofproliferation, induction of differentiation and induction or repression of gene expression.[1] As such, it can be used in lab to bring about any of these effects.

Compositions:
  • Bodybio Sodium Butyrate A short Chain fatty acid
  • Packing: 600 mg 100 capsules
  • Type: Capsules

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